Animal StudyPubMed ID: 11297605·2001

GH Receptor-Independent Lipolytic Activity of AOD 9604 in Growth Hormone Receptor-Deficient Mice

Hefti FF, Frazier-Higgins D, Duong TT, et al.

Endocrinology, 2001

Key finding

AOD 9604 reduced visceral fat by 24% in GH receptor-deficient mice, confirming GH-R independent lipolytic mechanism.

Summary

Study in GH receptor-knockout mice demonstrating AOD 9604 lipolytic activity independent of classical GH signaling.

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Related compound

AOD-9604L2

A modified fragment of human growth hormone studied for fat metabolism without the growth-promoting effects of full GH.

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