Human RCTPubMed ID: 11386538·2001

Long-term cardiac effects of MK-677: echocardiography and autonomic function

Makimattila S, Ballantyne CM, Matz J, et al.

Journal of Cardiovascular Pharmacology, 2001 · n = 48

Key finding

No change in LV mass, ejection fraction, or dimensions; mild heart rate increase of 2.1 ± 1.3 bpm; diastolic BP increased 3.2 ± 1.8 mmHg.

Summary

12-week study of MK-677 cardiac effects including echocardiographic parameters, heart rate variability, and blood pressure.

Read the study

The full citation, abstract, and (when available) the full text can be accessed on PubMed. PeptideMark summaries are condensed overviews — we encourage researchers to read primary sources.

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Related compound

MK-677L4

An oral ghrelin mimetic (not a peptide) that stimulates growth hormone release. Has extensive human data but has not achieved FDA approval.

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