Thymosin Beta-4 Regulates Cell Migration and Actin Polymerization in Corneal Epithelium
Sosne G, Kurpakus-Wheater M, Wheatley SB, et al.
Investigative Ophthalmology and Visual Science, 2002 · n = 6
Key finding
TB-500 increased corneal epithelial cell migration rate 4.7-fold, enhanced wound healing in vitro by 89%, and increased actin polymerization 2.3-fold.
Summary
TB-500 enhanced corneal epithelial cell migration and healing through actin-dependent mechanisms.
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