Animal StudyPubMed ID: 14554208·2003

Gastric pentadecapeptide BPC 157 accelerates healing of transected rat Achilles tendon and in vitro stimulates tendocytes growth

Staresinic M, Petrovic I, Novinscak T, et al.

Journal of Orthopaedic Research, 2003

Key finding

BPC-157 improved tendon recovery biomechanically (increased load of failure), functionally (higher AFI values), and microscopically (superior fibroblast and collagen formation) at all tested doses.

Summary

Rat study showing BPC-157 administered intraperitoneally at doses of 10 micrograms, 10 nanograms, or 10 picograms accelerated Achilles tendon healing with improved biomechanical properties and superior collagen formation.

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Related compound

BPC-157L2

A gastric pentadecapeptide studied extensively in animal models for tissue healing, gut protection, and cytoprotective properties. Despite over 100 preclinical studies, human clinical data remains extremely limited.

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