Animal StudyPubMed ID: 15052688·2004

Protective effects of pentadecapeptide BPC 157 on gastric ulcer in rats

Xue XC, Wu YJ, Gao MT, et al.

World Journal of Gastroenterology, 2004

Key finding

BPC-157 demonstrated significant gastroprotective effects, reducing gastric ulcer area and accelerating healing through both administration routes in rat models.

Summary

Rat study showing both intramuscular and intragastric BPC-157 reduced ulcer area and accelerated healing of induced gastric ulcers, with intramuscular administration showing superior results.

Read the study

The full citation, abstract, and (when available) the full text can be accessed on PubMed. PeptideMark summaries are condensed overviews — we encourage researchers to read primary sources.

View on PubMed

Related compound

BPC-157L2

A gastric pentadecapeptide studied extensively in animal models for tissue healing, gut protection, and cytoprotective properties. Despite over 100 preclinical studies, human clinical data remains extremely limited.

More research on BPC-157

Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review

Sports Health · 2025 · Review

Safety of Intravenous Infusion of BPC157 in Humans: A Pilot Study

Alternative Therapies in Health and Medicine · 2025 · Human Pilot

The Stable Gastric Pentadecapeptide BPC 157 Pleiotropic Beneficial Activity and Its Possible Relations with Neurotransmitter Activity

Pharmaceuticals · 2024 · Review

Stable Gastric Pentadecapeptide BPC 157 and Wound Healing

Frontiers in Pharmacology · 2021 · Review

Modulatory effects of BPC 157 on vasomotor tone and the activation of Src-Caveolin-1-endothelial nitric oxide synthase pathway

Scientific Reports · 2020 · Animal Study