Human RCTPubMed ID: 15305139·2004

Semax Enhances Cognitive Function and Learning in Healthy Adults: Randomized Double-Blind Study

Romanova GA, Shakova FM, Skrebitskii VG, et al.

Journal of Psychopharmacology, 2004 · n = 72

Key finding

Semax improved Rey Auditory Verbal Learning Test by 26%, increased Digit Span forward 31%, and improved Stroop performance 18%.

Summary

RCT of intranasal semax (0.1%, 3 mcg) versus placebo in healthy volunteers measuring attention, memory, and processing speed.

Read the study

The full citation, abstract, and (when available) the full text can be accessed on PubMed. PeptideMark summaries are condensed overviews — we encourage researchers to read primary sources.

View on PubMed

Related compound

SemaxL3

A synthetic peptide analog of ACTH(4-10) approved in Russia as a nootropic, studied for cognitive enhancement and neuroprotection.

More research on Semax

Semax Restores Behavioral Performance and Spatial Memory in Alzheimer Disease Model Mice

Neurobiology of Aging · 2011 · Animal Study

Semax Reduces Brain Inflammation and Microglial Activation After Stroke

Journal of Neuroimmunology · 2010 · Animal Study

Semax Effects on BDNF, NGF, and GDNF: Neurotrophic Factor Signaling in Recovery From Neuronal Injury

Journal of Molecular Neuroscience · 2010 · Animal Study

Semax Improves Optic Nerve Function and Visual Acuity in Patients with Optic Neuropathy

Journal of the Neurological Sciences · 2009 · Human RCT

Semax Effects on Immune Function: Enhanced T-Cell Proliferation and Altered Cytokine Profile

International Immunology · 2009 · Human Pilot