Animal StudyPubMed ID: 17326080·2007

TB-500 Protects Against Acute Liver Injury

Craven RJ, Xu LH, Weiner TM, et al.

Hepatology, 2007 · n = 38

Key finding

TB-500 reduced transaminase elevation by 81%, decreased hepatocyte apoptosis by 73%, improved survival from 25% to 82%.

Summary

TB-500 protected hepatocytes from LPS and D-galactosamine-induced acute liver injury.

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Related compound

TB-500L3

A naturally occurring peptide central to cell migration and tissue repair. Phase 2 human wound healing trials showed accelerated healing; also studied for cardiac and corneal repair.

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