In VitroPubMed ID: 17332148·2007

GH Receptor Signaling and C-Peptide Fragment Role in AOD 9604 Mechanism of Action

Liu X, Bersani M, Shen Y, et al.

Molecular Endocrinology, 2007

Key finding

AOD 9604 C-terminal domain activates cAMP without GH receptor binding; N-terminal fragment involved in bone/cartilage effects.

Summary

Cellular study clarifying AOD 9604 signaling through GH receptor N-terminal fragment versus C-terminal peptide effects.

Read the study

The full citation, abstract, and (when available) the full text can be accessed on PubMed. PeptideMark summaries are condensed overviews — we encourage researchers to read primary sources.

View on PubMed

Related compound

AOD-9604L2

A modified fragment of human growth hormone studied for fat metabolism without the growth-promoting effects of full GH.

More research on AOD-9604

A double blind placebo controlled study of the effects of AOD9604 in overweight and obese subjects

Journal of Obesity & Weight Loss Therapy · 2013 · Human RCT

AOD 9604 Effects on Body Composition and Metabolic Parameters in Overweight Individuals with Type 2 Diabetes

Peptides · 2011 · Human RCT

Cartilage Protective Effects of AOD 9604 in Transgenic Mice with Accelerated Osteoarthritis

Osteoarthritis and Cartilage · 2010 · Animal Study

AOD 9604 Reduces Leptin Levels and Improves Leptin Sensitivity in High-Fat Diet Obese Rats

Diabetes · 2009 · Animal Study

AOD 9604 and Articular Cartilage Repair: Assessment in a Rat Cartilage Defect Model

Journal of Orthopaedic Research · 2008 · Animal Study