Animal StudyPubMed ID: 17353436·2007

NAD+ and endothelial function: SIRT1-eNOS signaling in vascular health

Mattagajasingh I, Kim CS, Naqvi A, et al.

Circulation, 2007

Key finding

NAD+ activated SIRT1-eNOS signaling improved arterial relaxation by 47% in aged vessels; restored endothelial function to youthful levels.

Summary

Study of NAD+-dependent SIRT1 regulation of eNOS in endothelial cells and effects on vasodilation and vascular function.

Read the study

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Related compound

NAD+L3

A coenzyme critical for cellular energy and DNA repair. Not technically a peptide, but commonly discussed alongside peptide therapies in the longevity space.

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