In VitroPubMed ID: 17654752·2007

Semax Protects Against Glutamate Excitotoxicity and Oxidative Stress in Neuronal Cultures

Arushanian EB, Stepanov SS, Ashmarin IP.

Journal of Neuroscience Research, 2007

Key finding

Semax reduced glutamate-induced neurotoxicity 71%, decreased ROS production 68%, and inhibited caspase-3 activation by 64%.

Summary

In-vitro neuroprotection study examining semax effects on glutamate-induced excitotoxicity, ROS production, and neuronal apoptosis.

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Related compound

SemaxL3

A synthetic peptide analog of ACTH(4-10) approved in Russia as a nootropic, studied for cognitive enhancement and neuroprotection.

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