In VitroPubMed ID: 18165383·2008

Growth Hormone Fragment Peptide-Induced Lipolysis: Comparison of AOD 9604, HGH, and Thiazolidinediones

Liu X, Ng FM, Shen Y, et al.

Journal of Molecular Endocrinology, 2008

Key finding

AOD 9604 showed superior lipolytic activity (EC50 45 nM) versus native GH (EC50 380 nM) with insulin-independent mechanism.

Summary

Comparative in-vitro study of lipolytic potency and selectivity among AOD 9604, native GH, and common antidiabetic agents.

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Related compound

AOD-9604L2

A modified fragment of human growth hormone studied for fat metabolism without the growth-promoting effects of full GH.

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