Animal StudyPubMed ID: 19487356·2009

BPC-157 Promotes Angiogenesis and Vascular Stability in Ischemic Tissue

Mise S, Sikiric P, Draganov D, et al.

Vascular Medicine Review, 2009 · n = 42

Key finding

BPC-157 increased capillary density by 89% at week 3, improved blood flow by 71%, and reduced limb loss incidence from 85% to 12% (p<0.001).

Summary

BPC-157 stimulated neovascularization in ischemic hindlimb model with improved perfusion recovery and reduced tissue necrosis.

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Related compound

BPC-157L2

A gastric pentadecapeptide studied extensively in animal models for tissue healing, gut protection, and cytoprotective properties. Despite over 100 preclinical studies, human clinical data remains extremely limited.

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