Animal StudyPubMed ID: 19647084·2009

Thymosin Beta-4 Enhances Bone Healing in Fracture Model

Tkalcevic G, Zenko A, Horvat N, et al.

Bone, 2009 · n = 44

Key finding

TB-500 increased callus volume by 78%, bone mineral density by 45%, biomechanical strength by 62% versus untreated controls.

Summary

TB-500 accelerated fracture healing with improved callus formation and bone mineralization.

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Related compound

TB-500L3

A naturally occurring peptide central to cell migration and tissue repair. Phase 2 human wound healing trials showed accelerated healing; also studied for cardiac and corneal repair.

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