Animal StudyPubMed ID: 20514502·2010

Body Protective Compound BPC-157 Improves Mucosa Restitution in Acetic Acid-Induced Gastric Ulcer

Sikiric P, Seiwerth S, Grabarevic Z, et al.

Digestive Diseases and Sciences, 2010 · n = 56

Key finding

BPC-157 reduced ulcer area by 85% within 7 days versus 42% in controls; improved mucus secretion and reduced neutrophil infiltration (p<0.01).

Summary

BPC-157 enhanced gastric ulcer healing through accelerated epithelial restitution and reduced inflammatory infiltration in rat acetic acid-induced ulcer model.

Read the study

The full citation, abstract, and (when available) the full text can be accessed on PubMed. PeptideMark summaries are condensed overviews — we encourage researchers to read primary sources.

View on PubMed

Related compound

BPC-157L2

A gastric pentadecapeptide studied extensively in animal models for tissue healing, gut protection, and cytoprotective properties. Despite over 100 preclinical studies, human clinical data remains extremely limited.

More research on BPC-157

Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review

Sports Health · 2025 · Review

Safety of Intravenous Infusion of BPC157 in Humans: A Pilot Study

Alternative Therapies in Health and Medicine · 2025 · Human Pilot

The Stable Gastric Pentadecapeptide BPC 157 Pleiotropic Beneficial Activity and Its Possible Relations with Neurotransmitter Activity

Pharmaceuticals · 2024 · Review

Stable Gastric Pentadecapeptide BPC 157 and Wound Healing

Frontiers in Pharmacology · 2021 · Review

Modulatory effects of BPC 157 on vasomotor tone and the activation of Src-Caveolin-1-endothelial nitric oxide synthase pathway

Scientific Reports · 2020 · Animal Study