Animal StudyPubMed ID: 23462327·2013

BPC-157 Regulates Inflammatory Response in Acute Pancreatitis Model

Drmic D, Samara M, Novic L, et al.

Pancreas, 2013 · n = 36

Key finding

BPC-157 reduced amylase elevation by 76%, decreased IL-6 and TNF-α by 69% and 72% respectively, and preserved acinar architecture (p<0.001).

Summary

BPC-157 demonstrated anti-inflammatory effects in cerulein-induced acute pancreatitis with reduced cytokine release and gland preservation.

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Related compound

BPC-157L2

A gastric pentadecapeptide studied extensively in animal models for tissue healing, gut protection, and cytoprotective properties. Despite over 100 preclinical studies, human clinical data remains extremely limited.

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