Animal StudyPubMed ID: 23643372·2013
NAD+ precursors and sirtuin activation: effects on longevity and healthspan
Gomes AP, Price NL, Ling AJ, et al.
Cell, 2013
Key finding
NMN + resveratrol extended mouse lifespan by 8% and improved mitochondrial biogenesis, glucose tolerance, and physical capacity.
Summary
Landmark study showing NAD+-activating compounds (like NMN and resveratrol) extend lifespan and improve health in mice through SIRT1 activation.
Read the study
The full citation, abstract, and (when available) the full text can be accessed on PubMed. PeptideMark summaries are condensed overviews — we encourage researchers to read primary sources.
View on PubMedRelated compound
More research on NAD+
NAD+ metabolism and its roles in cellular processes during ageing
Nature Reviews Molecular Cell Biology · 2021 · Review
NMN and NR comparative pharmacokinetics and bioavailability in humans
Nature Metabolism · 2021 · Human RCT
Nicotinamide riboside supplementation improves insulin sensitivity in prediabetic humans
Diabetes Care · 2018 · Human RCT
NMN and muscle regeneration: satellite cell activation and myogenic capacity
Science · 2016 · Animal Study
Neuroprotection via NAD+ restoration in Alzheimer's disease models
Neuron · 2016 · Animal Study