Animal StudyPubMed ID: 23959739·2013

BPC-157 Restores Muscle Healing and Regeneration After Myotoxic Injury

Jagic V, Sikiric P, Seiwerth S, et al.

Journal of Physiology and Pharmacology, 2013 · n = 48

Key finding

BPC-157 increased myogenic gene expression (MyoD, Myogenin) 5.2-fold, improved muscle fiber diameter by 81%, and restored contractility (p<0.01).

Summary

Intragastric BPC-157 enhanced skeletal muscle regeneration following bupivacaine-induced myotoxic injury with improved fiber organization and strength.

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Related compound

BPC-157L2

A gastric pentadecapeptide studied extensively in animal models for tissue healing, gut protection, and cytoprotective properties. Despite over 100 preclinical studies, human clinical data remains extremely limited.

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