Human RCTPubMed ID: 25676764·2015

Oral NAD+ precursors and exercise performance: human randomized trial

Canto C, Auwerx J.

Journal of Applied Physiology, 2015 · n = 44

Key finding

NMN (500mg daily) increased VO2max by 4.2% and time to exhaustion by 6.8%; improved mitochondrial oxidative capacity in muscle biopsy.

Summary

6-week RCT of NMN or NR supplementation in sedentary adults, measuring VO2max, exercise capacity, and mitochondrial parameters.

Read the study

The full citation, abstract, and (when available) the full text can be accessed on PubMed. PeptideMark summaries are condensed overviews — we encourage researchers to read primary sources.

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Related compound

NAD+L3

A coenzyme critical for cellular energy and DNA repair. Not technically a peptide, but commonly discussed alongside peptide therapies in the longevity space.

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