Animal StudyPubMed ID: 33420028·2021

MOTS-c is an exercise-induced mitochondrial-encoded regulator of age-dependent physical decline and muscle homeostasis

Reynolds JC, et al.

Nature Communications, 2021

Key finding

MOTS-c treatment improved physical performance and muscle homeostasis in aged mice, mimicking some effects of exercise.

Summary

Study showing MOTS-c levels increase with exercise and administration improves physical capacity in aged mice.

Read the study

The full citation, abstract, and (when available) the full text can be accessed on PubMed. PeptideMark summaries are condensed overviews — we encourage researchers to read primary sources.

View on PubMed

Related compound

MOTS-cL2

A mitochondria-derived peptide that targets the AMPK pathway, studied for metabolic regulation and exercise mimicry.

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