MOTS-c effects on adipose tissue browning and thermogenic gene expression
Sripada L, Zhang H, Wakshlag JJ, et al.
International Journal of Obesity, 2024
Key finding
MOTS-c increased UCP1 protein expression in brown adipose tissue 2.7-fold and induced beige adipocyte markers in white adipose tissue; elevated core temperature 0.4°C.
Summary
Study examining MOTS-c effects on brown adipose tissue activation, beige adipocyte differentiation, and thermogenic marker expression (UCP1, PRDM16, PGC-1α).
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