Animal StudyPubMed ID: 38591827·2024

MOTS-c exercise mimetic effects in sedentary aged mice

Xiao T, Wang K, Ye Q, et al.

Journal of Gerontology: Series A, 2024

Key finding

MOTS-c recapitulated 68% of voluntary running metabolic benefits; improved glucose tolerance, increased running capacity, and enhanced mitochondrial biogenesis.

Summary

Study comparing MOTS-c treatment versus voluntary exercise in sedentary aged mice, measuring metabolic and physical function improvements.

Read the study

The full citation, abstract, and (when available) the full text can be accessed on PubMed. PeptideMark summaries are condensed overviews — we encourage researchers to read primary sources.

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Related compound

MOTS-cL2

A mitochondria-derived peptide that targets the AMPK pathway, studied for metabolic regulation and exercise mimicry.

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